Search results for "Injection solution"

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Physico-chemical stability of eribulin mesylate containing concentrate and ready-to-administer solutions.

2013

Objectives The aim of this study was to determine the stability of commercially available eribulin mesylate containing injection solution as well as diluted ready-to-administer solutions stored under refrigeration or at room temperature. Methods Stability was studied by a novel developed stability-indicating reversed-phase high-performance liquid chromatography (RP-HPLC) assay with ultraviolet detection (detection wavelength 200 nm). Triplicate test solutions of eribulin mesylate containing injection concentrate (0.5 mg/mL) and with 0.9% sodium chloride solution diluted ready-to-administer preparations (0.205 mg/mL eribulin mesylate in polypropylene (PP) syringes, 0.020 mg/mL eribulin mesyl…

Eribulin MesylateChromatographybusiness.industryReproducibility of ResultsInjection solutionPharmacologyKetonesHigh-performance liquid chromatographyPharmaceutical SolutionsOncologyDrug StabilityMedicinePharmacology (medical)Chemical stabilitybusinessFuransChromatography High Pressure LiquidDrug PackagingJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
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